Preimplantation Genetic Testing in India
When you want to lower the chance of passing on a genetic condition or reduce the risk of transferring an embryo with the wrong number of chromosomes preimplantation genetic testing adds a careful checkpoint to IVF. After embryos reach day five or six a few outer cells are gently removed and tested so only embryos that meet agreed criteria are considered for transfer.
Discover what this treats so that you can choose confidently
PGT helps lower the chance of transferring embryos with chromosomal problems or a known inherited disorder. After two pregnancy losses due to a balanced rearrangement Samira and Imran chose IVF with PGT in India. Transferring one tested embryo led to a calmer first trimester and the steady heartbeat they had hoped for. Results vary; the aim is clarity before transfer and a safer path forward.
Plain language terms you will see
PGT A checks for extra or missing chromosomes aneuploidy
PGT M checks for a specific single gene condition such as thalassemia or cystic fibrosis
PGT SR checks embryos when parents carry structural chromosome changes such as translocations
Biopsy removing a few outer trophectoderm cells from a blastocyst for testing
Mosaicism a mix of normal and abnormal cells requiring careful counseling
How the procedure works in simple steps
- Counseling and test planning confirm whether PGT A PGT M or PGT SR fits your history; PGT M or SR may need a family specific assay
- IVF and embryo culture stimulation retrieval and fertilization proceed; embryos grow to day five or six
- Embryo biopsy and freezing five to ten trophectoderm cells removed; embryo immediately vitrified while results are processed
- Genetic analysis next generation sequencing classifies embryos as euploid unsuitable aneuploid or sometimes mosaic
- Selection and transfer after review a single euploid embryo is thawed and transferred; suitable embryos can stay frozen for future use
Think of PGT like checking a map before a mountain hike the destination is the same but a detailed route reduces wrong turns and surprises.
Who should consider this and when to wait
- Known single gene condition in the family use PGT M
- Balanced translocation or inversion in either partner use PGT SR
- Recurrent implantation failure or repeated miscarriage where chromosomes are suspected consider PGT A
- Advanced maternal age and wish to reduce aneuploid transfer consider PGT A
Consider waiting when uterine issues like polyps adhesions or cavity distorting fibroids are untreated when embryo numbers are very limited when urgent cancer therapy needs fertility preservation first or when emotional and financial planning needs more time.
Which embryos would be prioritized if some are euploid and some are mosaic? What is the plan if no euploid embryo is available? Ask these during consultation.
Benefits and risks that you should understand
Potential benefits
- Reduces chance of transferring embryos with chromosomal abnormalities
- Allows selection against a specific inherited disorder in eligible couples
- Supports single embryo transfer while preserving success odds
- May lower miscarriage risk in selected groups
Possible risks and limits
- Small chance of embryo damage during biopsy uncommon in experienced hands
- No test can guarantee a healthy baby rare false positives or negatives occur
- Mosaic results can be complex and need expert counseling
- Added time and cost for testing and storage
- Not all miscarriages are chromosomal other factors may remain
Balanced decisions pair testing science with transparent counseling so expectations stay realistic and hopeful.
Cost overview without surprises
| Scenario | Hospital category | Approx cost USD |
|---|---|---|
| IVF with PGT A biopsy and testing up to 5 embryos | NABH accredited clinic | 5,500–7,200 |
| IVF with PGT M single gene setup plus testing 4–6 embryos | Advanced metro center | 6,800–8,800 |
| IVF with PGT SR for translocation carriers testing 4–6 embryos | Premium fertility institute | 7,200–9,500 |
| Additional embryos per sample beyond package and one year storage | All accredited centers | 250–450 per embryo and 150–300 storage |
Simple math Base IVF 3,300 + PGT A package for five embryos 2,000 + medicines 700 + scans and anesthesia 120 ≈ 6,120 USD. If three extra embryos are tested at 300 each add 900 USD. Final quotes depend on case details and require a personalized estimate.
Cost drivers include test type A versus M versus SR number of embryos biopsied need for custom family assay PGT M lab platform turnaround time storage and number of transfers.
How to compare hospitals and specialists with confidence
- Is biopsy done in house or sent to a partner lab and what is the turnaround time
- Audited outcomes by age band including euploid rate and live birth per embryo transferred
- Clear policy for mosaic embryos and documentation of decisions
- Single embryo transfer as default for safety
- Counseling and consent for PGT A PGT M PGT SR including plan if no euploid embryo is available
- Chain of custody for samples and data privacy practices
Which clinic shows real sample reports and explains how findings translate into action on transfer day? Clarity now prevents confusion later.
Questions people often ask before this treatment
Will PGT increase my chance of pregnancy
PGT can reduce transfers of unsuitable embryos and may lower miscarriage risk in selected groups. It does not create extra embryos but helps choose among those you have.
Is embryo biopsy safe
In experienced programs blastocyst biopsy has a low complication rate. Labs will share thaw survival and post biopsy outcomes.
What does a mosaic result mean
It indicates a mix of normal and abnormal cells. Some mosaic embryos may be considered for transfer after detailed counseling depending on type and level.
How long should I stay in India
For a fresh cycle with biopsy and frozen transfer plan eighteen to twenty four days for stimulation and retrieval then return for a scheduled frozen transfer once results are ready. Some stay through to transfer if timelines allow.
Will PGT M catch every mutation in a family
It targets the known variant and may use linked markers. Rare off target variants may not be detected; pre and post test counseling is essential.
Video testimonials from real patients
Watch IVF and PGT success stories on our YouTube channel. Hearing how other couples navigated choices and timelines can make the path feel clearer and less lonely.
Important care note so that every reader stays safe
Choose a center that performs embryo biopsy routinely uses validated vitrification and warming protocols and provides formal genetic counseling. Avoid guaranteed claims and prioritize single embryo transfer unless a specific medical reason suggests otherwise.
Medically reviewed by
Dr Aryan Malhotra
MBBS David Tvildiani Medical University Georgia
Radiation Oncology Resident Burdwan Medical College and Hospital
Registration number 95565
Dr Malhotra reviews fertility genetics pages so that statements remain accurate balanced and patient friendly.
Disclaimer
This page provides general education. Decisions about IVF and PGT must be made with a licensed fertility specialist and genetic counselor who reviewed your history and test results.
References
Watch patient videos
https://www.youtube.com/@TreatmentCost